Article

Human DNA replication initiation sites are specified epigenetically by oxidation of 5-methyl-deoxycytidine

2024-09-07

Abstract excerpt

<h4>Summary</h4> DNA replication initiates at tens of thousands of sites on the human genome during each S phase. However, no consensus DNA sequence has been found that specifies the locations of these replication origins. Here, we investigate modifications of human genomic DNA by density equilibrium centrifugation and DNA sequencing. We identified short discrete sites with increased density during quiescence and...

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Literature Corpus work: add6bc00-7f38-549a-bcb1-f26f5d0ae822
DOI: 10.1101/2024.09.06.611651

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Human DNA replication initiation sites are specified epigenetically by oxidation of 5-methyl-deoxycytidineDOI 10.1101/2024.09.06.611651Read

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