Article

Genome Architecture Leads a Bifurcation in Cell Identity

2017-06-18

Abstract excerpt

<h4>SUMMARY</h4> Genome architecture is important in transcriptional regulation and study of its features is a critical part of fully understanding cell identity. Altering cell identity is possible through overexpression of transcription factors (TFs); for example, fibroblasts can be reprogrammed into muscle cells by introducing MYOD1. How TFs dynamically orchestrate genome architecture and transcription as a cel...

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Literature Corpus work: 8b225b71-c48b-575a-996b-13bea9e1dd84
DOI: 10.1101/151555

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