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Article

Aligning single-cell developmental and reprogramming trajectories identifies molecular determinants of reprogramming outcome

2017-03-30

Abstract excerpt

Cellular reprogramming through manipulation of defined factors holds great promise for large-scale production of cell types needed for use in therapy, as well as for expanding our understanding of the general principles of gene regulation. MYOD-mediated myogenic reprogramming, which converts many cell types into contractile myotubes, remains one of the best characterized model system for direct conversion by defin...

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Literature Corpus work
4647aec7-889f-55c7-9443-6bd4f4a559ab
DOI
10.1101/122531
Open publication

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Aligning single-cell developmental and reprogramming trajectories identifies molecular determinants of reprogramming outcomeDOI 10.1101/122531
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