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Article

Transcription Factor-Directed Re-wiring of Chromatin Architecture for Somatic Cell Nuclear Reprogramming toward trans-Differentiation.

Molecular cell - 7 Nov 2019

Dall'Agnese Alessandra, Caputo Luca, Nicoletti Chiara, di Iulio Julia, Schmitt Anthony, Gatto Sole, Diao Yarui, Ye Zhen, Forcato Mattia, Perera Ranjan, Bicciato Silvio, Telenti Amalio, Ren Bing, Puri Pier Lorenzo

Abstract excerpt

MYOD-directed fibroblast trans-differentiation into skeletal muscle provides a unique model to investigate how one transcription factor (TF) reconfigures the three-dimensional chromatin architecture to control gene expression, which is otherwise achieved by the combinatorial activities of multiple TFs. Integrative analysis of genome-wide high-resolution chromatin interactions, MYOD and CTCF DNA-binding profile,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 31519520
DOI: 10.1016/j.molcel.2019.07.036
PMCID: PMC6842445

Genes

TF
CTCF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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