Article

Dynamic Reorganization of Developmental to Adult Genome Topology Controls the Initiation and Stabilization of the Human Muscle Stem Cell State

2026-01-25

Abstract excerpt

Developmental gene expression is under tight temporal and spatial control. This regulation is imparted by tissue specific enhancers that integrate developmental signals into transcriptional responses to allow for developmental progression. Often species specific, the enhancers that regulate human muscle progenitor and stem cell gene expression are currently unknown. Here, we define the 3D chromatin organization of...

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Literature Corpus work: 4e89e0e9-584e-5750-bd8f-d5beeb4b2dde
DOI: 10.64898/2026.01.23.701436

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