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Article

Epigenetic control of myogenic identity of human muscle stem cells in Duchenne muscular dystrophy

8 Nov 2024

Abstract excerpt

locus caused downregulation of its expression and loss of the myogenic fate. Re-expression of MEF2B in DMD-MuSCs restored their myogenic fate. MEF2B is key in the maintenance of myogenic identity in human MuSCs, which is altered in DMD.

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Identifiers

PMID: 39650736
DOI: 10.1016/j.isci.2024.111350

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