Article

Low-level repressive histone marks fine-tune stemness gene transcription in neural stem cells

2022-11-18

Abstract excerpt

Coordinated regulation of stemness gene activity by transcriptional and translational mechanisms poise stem cells for a timely cell-state transition during differentiation. Although important for all stemness-to-differentiation transitions, mechanistic understanding of the fine-tuning of stemness gene transcription is lacking due to the compensatory effect of translational control. We used intermediate neural prog...

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Identifiers and source

Literature Corpus work: 84837635-222f-509a-8933-c230b0724c45
DOI: 10.1101/2022.11.18.517130

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