Article

Massively parallel characterization of regulatory dynamics during neural induction

2018-07-16

Abstract excerpt

The molecular components governing neural induction remain largely unknown. Here, we applied a suite of genomic and computational tools to comprehensively identify these components. We performed RNA-seq, ChIP-seq (H3K27ac, H3K27me3) and ATAC-seq on human embryonic stem cells (hESCs) at seven early neural differentiation time points (0-72 hours) and identified thousands of induced genes and regulatory regions. We a...

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Literature Corpus work: e3e050ca-47a0-5c97-99c3-aacdecf13142
DOI: 10.1101/370452

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