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Article

The transcription factor Nerfin-1 prevents reversion of neurons into neural stem cells.

Genes & development - 15 Jan 2015

Froldi Francesca, Szuperak Milan, Weng Chen-Fang, Shi Wei, Papenfuss Anthony T, Cheng Louise Y

Abstract excerpt

Cellular dedifferentiation is the regression of a cell from a specialized state to a more multipotent state and is implicated in cancer. However, the transcriptional network that prevents differentiated cells from reacquiring stem cell fate is so far unclear. Neuroblasts (NBs), the Drosophila neural stem cells, are a model for the regulation of stem cell self-renewal and differentiation. Here we show that the...

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Identifiers

PMID: 25593306
DOI: 10.1101/gad.250282.114
PMCID: PMC4298133

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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