Article

Identifying regulators of neural stem cell fate and tumourigenesis

2018-01-01

Abstract excerpt

The proliferation of neural stem cells (NSCs) must be regulated precisely in order to generate a functional nervous system. Mis-regulated NSC division can lead to the inadequate production of differentiated progeny or to ectopic NSCs and tumour formation. As such, genes that promote the proliferative capacity of NSCs must be maintained in NSCs but down regulated in post-mitotic progeny. In vertebrates, the orphan...

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Literature Corpus work: a290b694-b6d2-5c34-a4a7-00c0d41d380f
DOI: 10.17863/cam.41367

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