Article

Classical driver mutations are not associated with metachronous lesion risk in patients undergoing post-polypectomy surveillance following removal of conventional adenomas in a bowel screening setting

2026-08-10

Abstract excerpt

<h4>Introduction</h4> Patients undergoing polypectomy at colonoscopy remain at risk of metachronous neoplasia despite surveillance guided by histopathological features. Mutational profiling of adenomas, including canonical driver mutations in APC, KRAS , and TP53 , may offer additional predictive value. This study aimed to determine whether mutational status in index adenomas was associated with metachronous le...

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Literature Corpus work: 818f2c72-d06a-545f-bbdc-38f616a7a197
DOI: 10.64898/2026.08.05.26359768

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