Article
KRAS and BRAF somatic mutations in colonic polyps and the risk of metachronous neoplasia.
PloS one - 1 Jan 2017
Juárez Miriam, Egoavil Cecilia, Rodríguez-Soler María, Hernández-Illán Eva, Guarinos Carla, García-Martínez Araceli, Alenda Cristina, Giner-Calabuig Mar, Murcia Oscar, Mangas Carolina, Payá Artemio, Aparicio José R, Ruiz Francisco A, Martínez Juan, Casellas Juan A, Soto José L, Zapater Pedro, Jover Rodrigo
Abstract excerpt
BACKGROUND & AIMS: High-risk features of colonic polyps are based on size, number, and pathologic characteristics. Surveillance colonoscopy is often recommended according to these findings. This study aimed to determine whether the molecular characteristics of polyps might provide information about the risk of metachronous advanced neoplasia. METHODOLOGY: We retrospectively included 308 patients with colonic...
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