Article

Low input capture Hi-C (liCHi-C) identifies promoter-enhancer interactions at high-resolution

2022-11-05

Abstract excerpt

Long-range interactions between regulatory elements and promoters are key in gene transcriptional control; however, their study requires large amounts of starting material, which is not compatible with clinical scenarios nor the study of rare cell populations. Here we introduce low input capture Hi-C (liCHi-C) as a cost-effective, flexible method to map and robustly compare promoter interactomes at high resolution...

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Literature Corpus work: 7c789b4b-2011-5b49-8d16-37f5ec0764b0
DOI: 10.1101/2022.11.04.515239

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