Article

CHiCAGO: Robust Detection of DNA Looping Interactions in Capture Hi-C data

2015-10-01

Abstract excerpt

<h4>ABSTRACT</h4> Capture Hi-C (CHi-C) is a state-of-the art method for profiling chromosomal interactions involving targeted regions of interest (such as gene promoters) globally and at high resolution. Signal detection in CHi-C data involves a number of statistical challenges that are not observed when using other Hi-C-like techniques. We present a background model, and algorithms for normalisation and multiple...

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Literature Corpus work: a980b53b-e0b6-5c63-b35c-2c40c8bf1aa5
DOI: 10.1101/028068

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