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Article

Chicdiff: a computational pipeline for detecting differential chromosomal interactions in Capture Hi-C data

2019-01-22

Abstract excerpt

<h4>Summary</h4> Capture Hi-C is a powerful approach for detecting chromosomal interactions involving, at least on one end, DNA regions of interest, such as gene promoters. We present Chicdiff, an R package for robust detection of differential interactions in Capture Hi-C data. ChiScdiff enhances a state-of-the-art differential testing approach for count data with bespoke normalisation and multiple testing proced...

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Literature Corpus work
7d774ca8-324e-533e-94d1-bef1a816acb1
DOI
10.1101/526269
Open publication

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Chicdiff: a computational pipeline for detecting differential chromosomal interactions in Capture Hi-C dataDOI 10.1101/526269
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