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Article

SnapHiC-G: identifying long-range enhancer-promoter interactions from single-cell Hi-C data via a global background model.

Briefings in bioinformatics - 25 Jul 2024

Liu Weifang, Zhong Wujuan, Giusti-Rodríguez Paola, Jiang Zhiyun, Wang Geoffery W, Sun Huaigu, Hu Ming, Li Yun

Abstract excerpt

Harnessing the power of single-cell genomics technologies, single-cell Hi-C (scHi-C) and its derived technologies provide powerful tools to measure spatial proximity between regulatory elements and their target genes in individual cells. Using a global background model, we propose SnapHiC-G, a computational method, to identify long-range enhancer-promoter interactions from scHi-C data. We applied SnapHiC-G to...

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Share to Computational Biology
Share to Enhancer Elements, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Genomics

Share to Polymorphism, Single Nucleotide

Share to Promoter Regions, Genetic

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Source

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Identifiers

PMID: 39222061
DOI: 10.1093/bib/bbae426
PMCID: PMC11367764

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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