Article

Static and dynamic DNA loops form AP-1 bound activation hubs during macrophage development

2017-05-25

Abstract excerpt

<h4>SUMMARY</h4> The three-dimensional arrangement of the human genome comprises a complex network of structural and regulatory chromatin loops important for coordinating changes in transcription during human development. To better understand the mechanisms underlying context-specific 3D chromatin structure and transcription during cellular differentiation, we generated comprehensive in situ Hi-C maps of DNA loop...

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Literature Corpus work: beac76d6-ab99-5294-89c2-a112d6471692
DOI: 10.1101/142026

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