Article

SnapHiC-G: identifying long-range enhancer-promoter interactions from single-cell Hi-C data via a global background model

2023-03-02

Abstract excerpt

Harnessing the power of single-cell genomics technologies, single-cell Hi-C (scHi-C) and its derived technologies provide powerful tools to measure spatial proximity between regulatory elements and their target genes in individual cells. Using a global background model, we propose SnapHiC-G, a computational method to identify long-range enhancer-promoter interactions from scHi-C data. We applied SnapHiC-G to scHi-...

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Literature Corpus work: d3c358a7-591c-5346-9852-551c73f66044
DOI: 10.1101/2023.03.01.530686

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