Article

UniversalEPI: robust prediction of cell type-specific and differential chromatin interactions from DNA sequence and chromatin accessibility

2024-11-23

Abstract excerpt

Enhancer–promoter interactions (EPIs) play a central role in gene regulation, but experimental techniques such as Hi-C for mapping these interactions remain costly and labor-intensive. Computational methods have been developed to predict EPIs in silico from DNA sequence and chromatin information; however, there are major challenges with the generalizability and accuracy of predictions by existing methods across ce...

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Literature Corpus work: 55f5dbcc-e92e-5f89-b3a9-3604e6a7b306
DOI: 10.1101/2024.11.22.624813

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