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Article

Analysis of hundreds of cis-regulatory landscapes at high resolution in a single, high-throughput experiment.

Nature genetics - 1 Feb 2014

Hughes Jim R, Roberts Nigel, McGowan Simon, Hay Deborah, Giannoulatou Eleni, Lynch Magnus, De Gobbi Marco, Taylor Stephen, Gibbons Richard, Higgs Douglas R

Abstract excerpt

Gene expression during development and differentiation is regulated in a cell- and stage-specific manner by complex networks of intergenic and intragenic cis-regulatory elements whose numbers and representation in the genome far exceed those of structural genes. Using chromosome conformation capt...

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PMID: 24413732
DOI: 10.1038/ng.2871

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24413732-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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