Article
Cell-cycle dependent DNA repair and replication unifies patterns of chromosome instability
2024-01-04
Abstract excerpt
Chromosomal instability (CIN) is pervasive in human tumours and often leads to structural or numerical chromosomal aberrations. Somatic structural variants (SVs) are intimately related to copy number alterations but the two types of variant are often studied independently. In addition, despite numerous studies on detecting various SV patterns, there are still no general quantitative models of SV generation. To add...
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Identifiers and source
- Literature Corpus work
- 72a0c479-7d63-5ba0-a431-26f5484a2760
- DOI
- 10.1101/2024.01.03.574048