Article

A CRISPR/Cas9 vector system for neutrophil-specific gene disruption in zebrafish

2020-07-28

Abstract excerpt

Tissue-specific knockout techniques are widely applied in biological studies to probe the tissue-specific roles of specific genes in physiology, development, and disease. CRISPR/Cas9 is a widely used technology to perform fast and efficient genome editing in vitro and in vivo. Here, we report a robust CRISPR-based gateway system for tissue-specific gene inactivation in zebrafish. A transgenic fish line expressing...

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Literature Corpus work: 6dd40e44-c91b-596a-b6cf-04bc5096749e
DOI: 10.1101/2020.07.27.223008

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