Article

Cell migration CRISPRi screens in human neutrophils reveal regulators of context-dependent migration and differentiation state

2022-12-16

Abstract excerpt

<h4>ABSTRACT</h4> Neutrophils are the most abundant leukocyte in humans and provide a critical early line of defense as part of our innate immune system. Their exquisite sensitivity to chemical gradients and ability to rapidly migrate make them especially suited to protect against infection. However, their terminal differentiation status and short lifetime (on the order of days) have hindered their study. Further...

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Literature Corpus work: 13bf0258-e42e-5584-bb74-0ee478a0977a
DOI: 10.1101/2022.12.16.520717

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