Article

A Joint Tau Propagation and Neuroinflammation Model Reinforces Inflammatory Modulation of Network-Driven Spread in Alzheimer’s Disease

2026-01-08

Abstract excerpt

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder and the leading cause of dementia. Despite over a century of research, AD remains untreatable due to an incomplete understanding of its underlying mechanisms. While amyloid beta has dominated therapeutic efforts, tau pathology and neuroinflammation represent critical disease drivers and intriguing therapeutic targets. We developed an extended com...

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Literature Corpus work: 5f5ade01-43a9-518d-b847-d376f61896c5
DOI: 10.64898/2026.01.07.698214

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