Article

Brain network dynamics determine tau presence while regional vulnerability governs tau load in Alzheimer’s disease

2025-04-23

Abstract excerpt

In Alzheimer’s disease (AD), tau pathology accumulates gradually throughout the brain, with clinical decline reflecting tau progression. A comprehensive understanding of, first, whether tau propagation is predominantly governed by connectome-based diffusion, regional vulnerability, or an interplay of both, and second, which types of brain connectivity or regional factors best explain tau propagation, remains cruci...

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Literature Corpus work: ba817bfa-f8d9-59e7-9bb2-843f1ed99ca5
DOI: 10.1101/2025.04.17.648358

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