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Article

Systematically understanding the key roles of microglia in AD development

2019-04-09

Abstract excerpt

Alzheimer’s disease (AD) is the leading cause of age-related dementia, affecting over 5 million people in the United States. Unfortunately, current therapies are largely palliative and several potential drug candidates have failed in late-stage clinical trials. Studies suggest that microglia-mediated neuroinflammation might be responsible for the failures of various therapies. Microglia contribute to Aβ clearance...

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Identifiers and source

Literature Corpus work
b3116ff6-1bbc-5bce-abc4-909f485cceb8
DOI
10.1101/601054
Open publication

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Systematically understanding the key roles of microglia in AD developmentDOI 10.1101/601054
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