Article

Brain network dynamics determine tau presence while regional vulnerability governs tau load in Alzheimer’s disease

2026-03-23

Abstract excerpt

<title>Abstract</title> <p>In Alzheimer’s disease (AD), tau pathology accumulates gradually throughout the brain, with clinical decline reflecting tau progression. A comprehensive understanding of, first, whether tau propagation is predominantly governed by connectome-based diffusion, regional vulnerability, or an interplay of both, and second, which types of brain connectivity or regional factors best explain ta...

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Literature Corpus work: d4aee779-afa1-5559-afd7-9293c7beb280
DOI: 10.21203/rs.3.rs-8687892/v1

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