Article

Rethinking Anti-Inflammatory Therapy in Alzheimer’s Disease: From Broad Suppression to Stage–State–Space Neuroimmune Reprogramming

2026-04-28

Abstract excerpt

Alzheimer’s Disease (AD) is now understood as a biologically diverse condition, with amyloid and tau pathology evolving within dynamic neuroimmune networks. This challenges the traditional view that AD-related inflammation can be broadly suppressed therapeutically. We review evidence showing that neuroinflammation in AD is stage-dependent, cell-state-specific, spatially organized, and functionally complex. Microgl...

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Literature Corpus work: e3c58083-5574-5a29-b6c1-2eefee8e16ac
DOI: 10.20944/preprints202604.1904.v1

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