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Genetically determined blood pressure, antihypertensive medications, and risk of Alzheimer’s disease: a Mendelian randomization study

2021-02-01

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> Observational studies suggest that the use of antihypertensive medications (AHMs) is associated with a reduced risk of Alzheimer’s disease (AD); however, these findings may be biased by confounding and reverse causality. We aimed to explore the effects of blood pressure (BP) and lowering systolic BP (SBP) via the protein targets of different AHMs on AD through a...

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Literature Corpus work
5a12b128-2046-57e5-82d2-b73546660373
DOI
10.21203/rs.3.rs-125105/v2
Open publication

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Genetically determined blood pressure, antihypertensive medications, and risk of Alzheimer’s disease: a Mendelian randomization studyDOI 10.21203/rs.3.rs-125105/v2
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