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Article

Dissecting the association between blood pressure traits, hypertension, antihypertensive medications and epilepsy: A Mendelian randomization study.

Epilepsy & behavior : E&B - 1 Dec 2024

Yu Cheng, Jiang Shijiu, Lv Bingjie, Deng Xuejun, Xu Da

Abstract excerpt

BACKGROUND: Observational studies suggest that hypertension and epilepsy have a high co-occurrence, and antihypertensive medications may have impacts on the prevention and treatment of epilepsy. However, the directionality of causation between them is elusive. METHOD: By leveraging genome-wide association studies (GWAS) summary data of each trait, we firstly performed bidirectional univariate Mendelian...

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PMID: 39541744
DOI: 10.1016/j.yebeh.2024.110140

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