Article

Angiotensin-converting enzyme inhibition and Alzheimer’s disease: Findings from proteome-wide Mendelian randomization and a large prospective cohort study

2024-09-24

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> We aimed to provide clinically translatable insights for drug discovery, repurposing, and vigilance for preventing Alzheimer’s disease (AD) by integrating genetic and “real-world” drug use data. <h4>Methods</h4> Proteome-wide Mendelian randomization (MR) analysis was conducted to identify plasma proteins causally related to AD risk using the largest summary-level data to date,...

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Literature Corpus work: 3ebd91d9-c8f3-567f-ba74-34a6c30047a5
DOI: 10.1101/2024.09.09.24313366

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