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Article

Association of antihypertensive drug target genes with alzheimer's disease: a mendelian randomization study.

Alzheimer's research & therapy - 10 Jan 2025

Zheng He, Chen Chaolei, Feng Yingqing

Abstract excerpt

BACKGROUND: Epidemiological and genetic studies have elucidated associations between antihypertensive medication and Alzheimer's disease (AD), with the directionality of these associations varying upon the specific class of antihypertensive agents. METHODS: Genetic instruments for the expression of antihypertensive drug target genes were identified using expression quantitative trait loci (eQTL) in blood, which...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39794838
DOI: 10.1186/s13195-025-01671-4
PMCID: PMC11720623

Genes

ACE

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