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Repurposing antihypertensive drugs for the prevention of Alzheimer’s disease: a Mendelian Randomization study

2018-12-13

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Evidence concerning the potential repurposing of antihypertensives for Alzheimer’s disease prevention is inconclusive. We used Mendelian randomization, which can be more robust to confounding by indication and patient characteristics, to investigate the effects of lowering systolic blood pressure (SBP), via different antihypertensive drug classes, on Alzheimer’s disease. <h4...

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Literature Corpus work
f11c64dc-ed78-5270-8be5-f026e412a3ae
DOI
10.1101/486878
Open publication

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Repurposing antihypertensive drugs for the prevention of Alzheimer’s disease: a Mendelian Randomization studyDOI 10.1101/486878
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