Article

SMYD2 Regulates Vascular Smooth Muscle Cell Phenotypic Switching and Intimal Hyperplasia via Interaction with Myocardin

2023-04-13

Abstract excerpt

<title>Abstract</title> <p>The SET and MYND domain-containing protein 2 (SMYD2) is a histone lysine methyltransferase that has been reported to regulate carcinogenesis and inflammation. However, its role in vascular smooth muscle cell (VSMC) homeostasis and vascular diseases has not been determined. Here, we investigated the role of SMYD2 in VSMC phenotypic modulation and vascular intimal hyperplasia and elucidat...

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Literature Corpus work: 58621931-84e5-5ae4-894c-076ccc14374b
DOI: 10.21203/rs.3.rs-2721176/v1

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