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Article

PRISM/PRDM6, a transcriptional repressor that promotes the proliferative gene program in smooth muscle cells.

Molecular and cellular biology - 1 Apr 2006

Davis Christopher A, Haberland Michael, Arnold Michael A, Sutherland Lillian B, McDonald Oliver G, Richardson James A, Childs Geoffrey, Harris Stephen, Owens Gary K, Olson Eric N

Abstract excerpt

Smooth muscle cells (SMCs) display remarkable phenotypic diversity and plasticity and can readily switch between proliferative and differentiated states in response to extracellular cues. In an effort to identify novel transcriptional regulators of smooth muscle phenotypes, we compared the gene expression profiles of arterial and venous SMCs by microarray-based transcriptional profiling. Among numerous genes...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 16537907
DOI: 10.1128/MCB.26.7.2626-2636.2006
PMCID: PMC1430312

Genes

PRDM6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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