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Article

Dedicator of cytokinesis 2, a novel regulator for smooth muscle phenotypic modulation and vascular remodeling.

Circulation research - 8 May 2015

Guo Xia, Shi Ning, Cui Xiao-Bing, Wang Jia-Ning, Fukui Yoshinori, Chen Shi-You

Abstract excerpt

RATIONALE: Vascular smooth muscle cell (SMC) phenotypic modulation and vascular remodeling contribute to the development of several vascular disorders such as restenosis after angioplasty, transplant vasculopathy, and atherosclerosis. The mechanisms underlying these processes, however, remain largely unknown. OBJECTIVE: The objective of this study is to determine the role of dedicator of cytokinesis 2 (DOCK2) in...

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Source

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Identifiers

PMID: 25788409
DOI: 10.1161/CIRCRESAHA.116.305863
PMCID: PMC4426039

Genes

DOCK2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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