Noncoding RNAs in smooth muscle cell homeostasis: implications in phenotypic switch and vascular disorders.

doi:10.1007/s00424-016-1821-x

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Article

Noncoding RNAs in smooth muscle cell homeostasis: implications in phenotypic switch and vascular disorders.

Pflugers Archiv : European journal of physiology - 1 Jun 2016

Coll-Bonfill N, de la Cruz-Thea B, Pisano M V, Musri M M

Abstract excerpt

Vascular smooth muscle cells (SMC) are a highly specialized cell type that exhibit extraordinary plasticity in adult animals in response to a number of environmental cues. Upon vascular injury, SMC undergo phenotypic switch from a contractile-differentiated to a proliferative/migratory-dedifferentiated phenotype. This process plays a major role in vascular lesion formation and during the development of vascular...

Topics

Animals
Homeostasis
Humans
MicroRNAs
Myocytes, Smooth Muscle
Phenotype
RNA, Long Noncoding
Vascular Diseases

Source

Open in PubMed

Identifiers

PMID: 27109570
DOI: 10.1007/s00424-016-1821-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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