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Article

Epigenetic Control of Smooth Muscle Cell Identity and Lineage Memory.

Arteriosclerosis, thrombosis, and vascular biology - 1 Dec 2015

Gomez Delphine, Swiatlowska Pamela, Owens Gary K

Abstract excerpt

Vascular smooth muscle cells (SMCs), like all cells, acquire a cell-specific epigenetic signature during development that includes acquisition of a unique repertoire of histone and DNA modifications. These changes are postulated to induce an open chromatin state (referred to as euchromatin) on the repertoire of genes that are expressed in differentiated SMC, including SMC-selective marker genes like Acta2 and...

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Identifiers

PMID: 26449751
DOI: 10.1161/ATVBAHA.115.305044
PMCID: PMC4662608

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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