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Cross-platform proteomics to advance genetic prioritisation strategies

2021-03-19

Abstract excerpt

<h4>ABSTRACT</h4> Discovery of protein quantitative trait loci (pQTLs) has been enabled by affinity-based proteomic techniques and is increasingly used to guide genetically informed drug target evaluation. Large-scale proteomic data are now being created, but systematic, bidirectional assessment of platform differences is lacking, restricting clinical translation. We compared genetic, technical, and phenotypic de...

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Literature Corpus work
55706845-1c7a-5322-9830-c0ab0407825a
DOI
10.1101/2021.03.18.435919
Open publication

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Cross-platform proteomics to advance genetic prioritisation strategiesDOI 10.1101/2021.03.18.435919
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