Article

Nanoparticle enriched mass spectrometry proteomics in British South Asians identifies novel variant-protein-disease mechanisms

2025-08-13

Abstract excerpt

<h4>ABSTRACT</h4> Understanding genetic variation underlying differences in plasma protein levels can elucidate human disease mechanisms, but prior evidence was almost entirely derived from white Europeans using protein-preselected affinity reagents. Here, we integrate exome sequencing and common non-coding variation with untargeted nanoparticle enriched mass spectrometry (MS)-based plasma proteomics (Seer Proteo...

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Literature Corpus work: 372bbc84-4172-5d58-89ea-6417c444414d
DOI: 10.1101/2025.08.12.25333522

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Nanoparticle enriched mass spectrometry proteomics in British South Asians identifies novel variant-protein-disease mechanismsDOI 10.1101/2025.08.12.25333522Read

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