Article

Efficient candidate drug target discovery through proteogenomics in a Scottish cohort

2024-01-30

Abstract excerpt

Understanding the genomic basis of human proteomic variability provides powerful tools to probe potential causal relationships of proteins and disease risk, and thus to prioritise candidate drug targets. Here, we investigated 6432 plasma proteins (1533 previously unstudied in large-scale proteomic GWAS) using the SomaLogic (v4.1) aptamer-based technology in a Scottish population from the Viking Genes study. A tota...

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Literature Corpus work: 0a453041-d81f-5c57-a6a4-77c39f6db7e8
DOI: 10.1101/2024.01.29.24301808

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