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Genetic determinants of the human plasma proteome and their application in biology and disease

2017-01-01

Abstract excerpt

Proteins are the primary functional units of biology and the direct targets of most drugs, yet there is limited knowledge of the genetic factors determining inter-individual variation in protein levels (protein quantitative trait loci (pQTLs)). Limitations in high-throughput proteomic measurement technology have meant well-powered genome-wide association studies for large number of proteins so far have lagged behi...

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Literature Corpus work
26a970f3-9147-545f-88ed-18ae6e190864
DOI
10.17863/cam.15487
Open publication

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