Article

Connecting genetic risk to disease endpoints through the human blood plasma proteome

2016-11-09

Abstract excerpt

Genome-wide association studies (GWAS) with intermediate phenotypes, like changes in metabolite and protein levels, provide functional evidence for mapping disease associations and translating them into clinical applications. However, although hundreds of genetic risk variants have been associated with complex disorders, the underlying molecular pathways often remain elusive. Associations with intermediate traits...

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Literature Corpus work: 505590e3-510e-51a1-8b65-78bf7b62d8e3
DOI: 10.1101/086793

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