Article

Early clonal expansion of tumor-infiltrating lymphocytes predicts response to immune checkpoint therapy

2022-05-20

Abstract excerpt

<title>Abstract</title> <p>Immune checkpoint therapy (ICT) causes durable tumor responses in a subgroup of patients. Profiling T cell receptor beta (TCRβ) repertoire structure in ICT responders and non-responders provides mechanistic insight into what constitutes an effective anti-tumor response, and could result in the development of predictive biomarkers of response to identify and stratify patients for ICT. To...

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Literature Corpus work: 50ebd3f1-a122-5856-9909-04e65ccb4563
DOI: 10.21203/rs.3.rs-1613398/v1

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