Article

A conserved subset of cold tumors responsive to immune checkpoint blockade

2024-03-08

Abstract excerpt

<h4>Background</h4> The efficacy of immune checkpoint blockade (ICB) depends on restoring immune recognition of cancer cells that have evaded immune surveillance. At the time of diagnosis, patients with lymphocyte-infiltrated cancers are the most responsive to ICB, yet a considerable fraction of patients have immune-poor tumors. <h4>Methods</h4> We analyzed transcriptomic data from IMvigor210, TCGA, and TISMO da...

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Literature Corpus work: f0e5f30d-246d-524a-a5ef-05dfe713fc3a
DOI: 10.1101/2024.03.06.583752

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