Article

DNA polymerase ζ is a robust reverse transcriptase

2024-09-28

Abstract excerpt

Cell biology and genetic studies have demonstrated that DNA double strand break (DSB) repair can be performed using an RNA transcript that spans the site of the DNA break as a template for repair. This type of DSB repair requires a reverse transcriptase to convert an RNA sequence into DNA to facilitate repair of the break, rather than copying from a DNA template as in canonical DSB repair. Translesion synthesis (T...

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Literature Corpus work: 49bdba7c-3b5b-50a6-b25c-db16cc573fc5
DOI: 10.1101/2024.09.27.615452

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