Article
A third essential DNA polymerase in S. cerevisiae.
Cell - 21 Sept 1990
Morrison A, Araki H, Clark A B, Hamatake R K, Sugino A
Abstract excerpt
DNA polymerases I and III are essential for viability of S. cerevisiae. We have cloned and analyzed POL2, the gene encoding the catalytic subunit of the third nuclear DNA polymerase, DNA polymerase II. POL2 expressed a transcript of approximately 7.5 kb and contained a reading frame that encoded a protein of calculated Mr 255,649. The N-terminal half of the predicted protein displayed relatively weak similarity...
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