Article
The fidelity of DNA synthesis by yeast DNA polymerase zeta alone and with accessory proteins.
Nucleic acids research - 1 Jan 2006
Zhong Xuejun, Garg Parie, Stith Carrie M, Nick McElhinny Stephanie A, Kissling Grace E, Burgers Peter M J, Kunkel Thomas A
Abstract excerpt
DNA polymerase zeta (pol zeta) participates in several DNA transactions in eukaryotic cells that increase spontaneous and damage-induced mutagenesis. To better understand this central role in mutagenesis in vivo, here we report the fidelity of DNA synthesis in vitro by yeast pol zeta alone and wi...
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