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Article

Biochemical properties of Saccharomyces cerevisiae DNA polymerase IV.

The Journal of biological chemistry - 20 May 2005

Bebenek Katarzyna, Garcia-Diaz Miguel, Patishall Steven R, Kunkel Thomas A

Abstract excerpt

Although mammals encode multiple family X DNA polymerases implicated in DNA repair, Saccharomyces cerevisiae has only one, DNA polymerase IV (pol IV). To better understand the repair functions of pol IV, here we characterize its biochemical properties. Like mammalian pol beta and pol lambda, but not pol mu, pol IV has intrinsic 5'-2-deoxyribose-5-phosphate lyase activity. Pol IV has low processivity and can fill...

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Identifiers

PMID: 15778218
DOI: 10.1074/jbc.M501981200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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