Article
Defining the divergent enzymatic properties of RNA polymerases I and II.
The Journal of biological chemistry - 1 Jan 2000
Jacobs Ruth Q, Ingram Zachariah M, Lucius Aaron L, Schneider David A
Abstract excerpt
Eukaryotes express at least three nuclear DNA-dependent RNA polymerases (Pols) responsible for synthesizing all RNA required by the cell. Despite sharing structural homology, they have functionally diverged to suit their distinct cellular roles. Although the Pols have been studied extensively, direct comparison of their enzymatic properties is difficult because studies are often conducted under disparate...
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